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Wydanie 3/2019
str. 19 - 23

Zapalenie błony naczyniowej w przebiegu sarkoidozy

Uveitis in Sarcoidosis

Katarzyna Jadczyk-Sorek ^1,2,3, Julia Janiszewska-Salamon ^1,2,3, Wojciech Luboń ², Ewa Mrukwa-Kominek ^1,2

¹Klinika Okulistyki Katedry Okulistyki Śląskiego Uniwersytetu Medycznego w Katowicach Kierownik: prof. dr hab. n. med. Ewa Mrukwa-Kominek
² Oddział Okulistyki Dorosłych Uniwersyteckie Centrum Kliniczne im. prof. K. Gibińskiego Śląskiego Uniwersytetu Medycznego w Katowicach
Kierownik: prof. dr hab. n. med. Ewa Mrukwa-Kominek
³ Szkoła Doktorska Wydziału Nauk Medycznych w Katowicach Śląskiego Uniwersytetu Medycznego w Katowicach
Kierownik: prof. dr hab. n. med. Ewa Obuchowicz

Summary: Sarcoidosis is a multi-system inflammatory disease of idiopathic etiology, which is characterized by pathological non-serous granulomas. Ocular sarcoidosis can develop as an isolated disease without a systemic form of the disease, or it can be the main place for the manifestation of symptoms. Uveitis is the main manifestation of the ocular sarcoidosis. Due to the lack of sensitive and specific diagnostic tests and the heterogeneity of the presented clinical symptoms, the diagnosis and treatment of sarcoidosis is difficult. Tissue biopsy is the gold diagnostic standard for making the final diagnosis. Due to the low availability and invasive character of the biopsy, for the determination of diagnosis of uveitis based on clinical symptoms and laboratory results, diagnostic criteria for ocular sarcoidosis were established on International Workshop on Ocular Sarcoidosis (IWOS). In the differential diagnosis various etiologic factors should be considered depending on the location of uveitis. As a result of chronic inflammation, cataracts, glaucoma, band keratopathy, cystoid macular oedema, choroidal neovascularization, vitreous haemorrhage, and oedema of the optic nerve disc may develop. The treatment is based mainly on the use of topical or general glucocorticosteroids and other immunomodulatory drugs. The prognosis for patients treated for uveitis varies, depends on the time of detection and implementation of appropriate therapy.

Słowa kluczowe: sarkoidoza oczna, zapalenie błony naczyniowej, IWOS, ziarniniaki.

Keywords: ocular sarcoidosis, uveitis, IWOS, granulomas.

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