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Wydanie 3/2005

Wzrokowe potencjały wywołane po brachyterapii przytarczowych czerniaków naczyniówki - doniesienie wstępne

Visual Evoked Potentials after Juxtapapillary Choroidal Melanoma Brachytherapy - Preliminary Report

Arkadiusz Pogrzebielski, Anna Piwowarczyk, Małgorzata Werenowska-Pietrzyk, Bożena Romanowska-Dixon

Katedra i Klinika Okulistyki Collegium Mediucm Uniwersytetu Jagiellońskiego w Krakowie Kierownik: dr hab. n. med. Bożena Romanowska-Dixon

Summary: Aim: Assessment of the influence of juxtapapillary choroidal melanoma brachytherapy on VEP results.
Material and methods: We examined 5 patients (3 women, 2 men) aged 23-73 lat (mean 61.8) with intraocular tumors located 0-3 mm from optic disc. Tumor thickness measured using USG was 3-8.3 mm (mean 4.9 mm). In 4 patients we used Ru-106 brachytherapy, in 1 patient I-125. In all patients before treatment and 1 moth later we performed fVEP, in 3 patients pVEP (Tomey).
Results: P100 amplitude fVEP before treatment was 4.5-30 µV (mean 14.06 µV), after treatment 6.3-28.6 µV (mean 13.28 µV). P100 latency before treatment was 110.1-143.8 ms (mean 122.22 ms), after treatment 110.2-50.6 ms (mean 132.76 ms). P100 amplitude pVEP before treatment was 5.5-12.2 µV (mean 8.4 µV), after treatment 4.2-7.3 V (mean 6.1 µV). P100 latency pVEP before treatment was 94.1-109.8 ms (mean 101.13 ms), after treatment 93-125.6 ms (mean 106.46 ms).
Conclusion: Both in fVEP and in pVEP we observed small decrease in P100 amplitude and increase in P100 latency, more pronounced in pVEP. These results need longer observation.

Keywords: VEP, choroidal melanoma, juxtapapillary melanoma.

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