Wydanie 1/2008

Czynniki miejscowe i ogólnoustrojowe wpływające na powstanie i utrzymywanie się makulopatii cukrzycowej w przebiegu cukrzycy typu 2. u pacjentów z prawidłowo uregulowanymi parametrami ogólnoustrojowymi - doświadczenia wsłasne

Local and General Factors Influencing Macular Edema Development and Persistence in Patients with INDDM and Good General Parameters - Own Experiences

Agnieszka Nowosielska, Iwona Grabska-Liberek

Oddział Kliniczny Okulistyki Centrum Medycznego Kształcenia Podyplomowego w Warszawie Samodzielny Publiczny Szpital Kliniczny im. prof. W. Orłowskiego w Warszawie P. o. kierownik: dr hab. n. med. Iwona Grabska-Liberek

Summary: Diabetic macular edema is the leading cause of blindness in patients below 50 years of age. Clinically significant macular edema may be present at each level of diabetic retinopathy and if untreated usually leads to gradual vision loss.
Based of clinical investigations performed we are aware that macular edema development is more frequent in patients with NIDDM, depends on diabetes duration, blood glucose level, and is more prevalent in patients with unstable hypertension.
Purpose: The aim of this paper is to identify and verify the causes of CSME in patients treated in Retinal Department of Ophthalmology Clinic at the Medical Center of Postgraduate Education.
Material and methods: We analyzed medical data of 194 eyes of 97 patients with NIDDM and other concomitant systemic conditions, but overall good biochemical control assessed by their General Practitioners.
Results: In the studied population there was no correlation between CSME presence and patients age, diabetes duration or retinopathy stage.
CSME occurred more frequently in eyes with no posterior vitreous detachment and that correlation was statistically significant (p=0.004).
We also noted that diffuse macular edema and cystoid macular edema were more prevalent in eyes with no PVD.
Conclusion: Based on the performed study, PVD should be considered as very important local factor of the CSME development in diabetic eyes.

Keywords: diabetes mellitus, diabetic macular edema, hypertension, clinically significant macular edema, posterior vitreous detachment.