Wydanie 4/2008
str. 50
Metoda sieciowania włókien kolagenowych w terapii stożka rogówki
Corneal Cross-Linking in Keratoconus Therapy
Radosław Dyszak1, Stanisława Gierek-Ciaciura1.2, Piotr Kucharzewski1, Ewa Mrukwa-Kominek1,2
1 Samodzielny Publiczny Szpital Kliniczny Nr 5
Śląskiego Uniwersytetu Medycznego w Katowicach
2 Klinika Okulistyki Katedry Okulistyki Śląskiego
Uniwersytetu Medycznego w Katowicach
Po. Ordynator: dr hab. n. med. Ewa Mrukwa-Kominek
Summary: Purpose: To
evaluate the clinical results of corneal cross-linking
in keratoconus therapy.
Material and Methods: We treated 37 eyes of 37
patients with progressive early and moderate state of
keratoconus. We examined non corrected visual acuity (VSC),
best spherical corrected visual acuity (BSCVA), best
corrected visual acuity (BCVA), keratometry (K1, K2 i
Kmin), pachymetry and endothelial cells mount. We
applied riboflavin solution on the cornea after removal
of the epithelium for 30 min. Then it was irradiated
with UVA (365 nm, 3 mW/cm2) at a distance of 4 cm for
next 30 min. Finally we applied contact lens and
prescribed antibiotic eye drops and dexpanthenol gel.
Post-operative controls were researched in 5 days, 2
weeks and 1, 3, 6 and 9 months after surgery.
Results: Progression of keratectasia was stopped
in all patients. Corneal transparency and endothelial
cells remained unchanged within the follow-up time in
all patients. No negative side effects were observed.
Conclusions: Collagen cross-linking might be a
useful treatment to stop the progression of keratoconus
and might prevent from keratoplasty. Further studies are
should exclude long-term side effects and evaluate the
long term durability of the mechanical stiffness effect.
Słowa kluczowe: zabieg sieciowania włókien kolagenowych rogówki, CCL, CXL, stożek rogówki, ryboflawina, rogówka.
Keywords: cross-linking, CXL, CCL, keratoconus, riboflavin, cornea.
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