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Wydanie 3/2007

Mikroskopia konfokalna rogówki w śródbłonkowym zespole tęczówkowo-rogówkowym

Confocal Microscopy of Cornea in Iridocorneal Endothelial Syndrome

Jacek P. Szaflik, Monika Udziela, Anna Kamińska, Anna Zaleska-Żmijewska, Urszula Kołodziejska, Jerzy Szaflik

Katedra i Klinika Okulistyki II Wydziału Lekarskiego Akademii Medycznej w Warszawie Samodzielny Publiczny Kliniczny Szpital Okulistyczny w Warszawie Kierownik: prof. dr hab. n. med. Jerzy Szaflik

Summary: Aim: To describe corneal confocal microscopy findings in cases of iridocorneal endothelial syndrome (ICE). Methods: 4 patients (3 men and 1 woman) aged 48-71 years (mean 56) were diagnosed. The ophthalmic examination was carried out including visual acuity, slit lamp biomicroscopy, fundus examination, tonometry, gonioscopy, pachymetry and confocal microscopy of the cornea. In 2 cases anterior segment optical coherence tomography was performed. Results: Slit lamp biomicroscopy revealed discrete, usually linear lesions on the posterior surface of the cornea. In vivo confocal microscopy imaged characteristic epithelium-like endothelial cells and stromal oedema usually limited to the area adjacent to the pathological endothelium. Conclusions: Presented cases confirm the clinical usefulness of confocal microscopy in the evaluation of endothelial pathologies. In-vivo confocal microscopy allows imaging the specific histopathologic corneal features of ICE syndrome also in its early stage, when changes are limited to cornea.

Keywords: iridocorneal endothelial syndrome, cornea, confocal microscopy, endothelium, glaucoma

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